Neural regulation of hypoxia-inducible factors and redox state drives the pathogenesis of hypertension in a rodent model of sleep apnea

Keyphrases

• Hypertension 100%
• HIF-2 100%
• Sleep Apnea 100%
• Redox State 100%
• Rodent Models 100%
• Hypoxia-inducible factor-1α (HIF-1α) 100%
• Hypoxia-inducible Factor 100%
• Neural Regulation 100%
• Obstructive Sleep Apnea 75%
• Carotid Body 75%
• Ca2+ 50%
• Brainstem 50%
• Reactive Oxygen Species 50%
• Sympathetic Nervous System 50%
• Chronic Intermittent Hypoxia 50%
• Synapse 25%
• Neurotransmitters 25%
• Catecholamines 25%
• Blood Pressure 25%
• Intracellular Calcium 25%
• Reactive Oxygen Species Level 25%
• Most Common Cause 25%
• Sympathetic Neurons 25%
• Sensory Nerves 25%
• Nucleus Tractus Solitarius 25%
• Rostral Ventrolateral Medulla 25%
• Interneuron 25%
• Epinephrine and Norepinephrine 25%
• Homeostasis 25%
• Western Societies 25%
• Glomus Cells 25%
• Pro-oxidant 25%
• Superoxide Dismutase 2 (SOD2) 25%
• O2 Sensing 25%
• Antioxidant Enzymes 25%
• Feed-forward Mechanism 25%
• NADPH Oxidase 2 (NOX2) 25%
• Adrenal Medulla 25%
• Homeostatic Balance 25%

Neuroscience

• Obstructive Sleep Apnea 100%
• Hypoxia-Inducible Factors 100%
• Reactive Oxygen Species 60%
• Carotid Body 60%
• Brainstem 40%
• Sympathetic Nervous System 40%
• Catecholamine 20%
• Neurotransmitter 20%
• Synapse 20%
• Epinephrine 20%
• Antioxidant 20%
• Norepinephrine 20%
• Medulla 20%
• Interneuron 20%
• Glomus Cell 20%
• Adrenal Medulla 20%