‘Nervous’ Immunity: Walking the Tightrope

Subhash Kulkarni; Sravya Kurapati; Milena Bogunovic

doi:10.1016/j.it.2020.03.009

‘Nervous’ Immunity: Walking the Tightrope

Subhash Kulkarni, Sravya Kurapati, Milena Bogunovic

School of Medicine

Research output: Contribution to journal › Short survey › peer-review

Abstract

There is a major gap in our understanding of how the intestinal immune and nervous systems are integrated to regulate protective adaptations to enteric infections while maintaining tissue homeostasis. Three recent complementary reports published in Cell (2020) provide new mechanistic insights into how this enteric neuro-immune crosstalk may occur.

Original language	English (US)
Pages (from-to)	359-362
Number of pages	4
Journal	Trends in Immunology
Volume	41
Issue number	5
DOIs	https://doi.org/10.1016/j.it.2020.03.009
State	Published - May 2020

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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title = "{\textquoteleft}Nervous{\textquoteright} Immunity: Walking the Tightrope",

abstract = "There is a major gap in our understanding of how the intestinal immune and nervous systems are integrated to regulate protective adaptations to enteric infections while maintaining tissue homeostasis. Three recent complementary reports published in Cell (2020) provide new mechanistic insights into how this enteric neuro-immune crosstalk may occur.",

author = "Subhash Kulkarni and Sravya Kurapati and Milena Bogunovic",

note = "Funding Information: S.K. is supported by a grant from the Ludwig Foundation and a pilot award from the Hopkins Digestive Diseases Basic & Translational Research Core Center grant P30DK089502 ; M.B. is supported by the Kenneth Rainin Foundation Innovation Award, NIAID AI126351-01 and NIDDK DK107603-01A1 . Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",

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AU - Kulkarni, Subhash

AU - Kurapati, Sravya

AU - Bogunovic, Milena

N1 - Funding Information: S.K. is supported by a grant from the Ludwig Foundation and a pilot award from the Hopkins Digestive Diseases Basic & Translational Research Core Center grant P30DK089502 ; M.B. is supported by the Kenneth Rainin Foundation Innovation Award, NIAID AI126351-01 and NIDDK DK107603-01A1 . Publisher Copyright: © 2020 Elsevier Ltd

PY - 2020/5

Y1 - 2020/5

N2 - There is a major gap in our understanding of how the intestinal immune and nervous systems are integrated to regulate protective adaptations to enteric infections while maintaining tissue homeostasis. Three recent complementary reports published in Cell (2020) provide new mechanistic insights into how this enteric neuro-immune crosstalk may occur.

AB - There is a major gap in our understanding of how the intestinal immune and nervous systems are integrated to regulate protective adaptations to enteric infections while maintaining tissue homeostasis. Three recent complementary reports published in Cell (2020) provide new mechanistic insights into how this enteric neuro-immune crosstalk may occur.

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JO - Trends in Immunology

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‘Nervous’ Immunity: Walking the Tightrope

Abstract

ASJC Scopus subject areas

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