@article{47ec37cfca354130a6197abfe6a82c25,
title = "Neighborhood greenspace and cognition: The cardiovascular health study",
abstract = "Objectives: We examined whether greenspace measures (overall percent greenspace and forest, and number of greenspace types) were associated with clinically adjudicated dementia status. Methods: In a sample of non-demented older adults (n = 2141, average age = 75.3 years) from the Cardiovascular Health and Cognition Study, Cox proportional hazard and logistic regression analyses were used to estimate associations of baseline greenspace with risks of incident dementia and MCI, respectively, while adjusting for demographics, co-morbidities, and other neighborhood factors. We derived quartiles of percent greenness (greenspace), forest (percent tree canopy cover), and tertiles of greenspace diversity (number of greenspace types) for 5-km radial buffers around participant's residences at study entry (1989–1990) from the 1992 National Land Cover Dataset. Dementia status and mild cognitive impairment (MCI) over 10 years was clinically adjudicated. Results: We observed no significant association between overall percent greenspace and risk of mild cognitive impairment or dementia and mostly null results for forest and greenspace diversity. Forest greenspace was associated with lower odds of MCI (OR quartile 4 versus 1: 0.54, 95% CI: 0.29–0.98) and greenspace diversity was associated with lower hazard of incident dementia (HR tertile 2 versus 1: 0.70, 95% CI = 0.50–0.99). Discussion: We found divergent results for different types of greenspace and mild cognitive impairment or dementia. Improved greenspace type and diversity measurement could better characterize the association between greenspace and cognition.",
keywords = "Alzheimer's disease, Environment, Epidemiology",
author = "Godina, {Sara L.} and Rosso, {Andrea L.} and Hirsch, {Jana A.} and Besser, {Lilah M.} and Lovasi, {Gina S.} and Donovan, {Geoffrey H.} and Garg, {Parveen K.} and Platt, {Jonathan M.} and Fitzpatrick, {Annette L.} and Lopez, {Oscar L.} and Carlson, {Michelle C.} and Michael, {Yvonne L.}",
note = "Funding Information: This work was supported by contracts HHSN268201200036C, HHSN268200800007C, HHSN268201800001C, N01HC55222, N01HC85079, N01HC85080, N01HC85081, N01HC85082, N01HC85083, N01HC85086, 75N92021D00006, and grants U01HL080295 and U01HL130114 from the National Heart, Lung, and Blood Institute ( NHLBI ), with additional contribution from the National Institute of Neurological Disorders and Stroke ( NINDS ). Additional support was provided by R01AG15928 , R01AG20098 , R01AG023629 , and R01AG055404 from the National Institute on Aging (NIA) . A full list of principal CHS investigators and institutions can be found at CHS-NHLBI.org . Incorporation of geographic characteristics was supported by the National Institute of Aging (grants 1R01AG049970 , 3R01AG049970-04S1 ), Commonwealth Universal Research Enhancement (C.U.R.E) program funded by the Pennsylvania Department of Health—2015 Formula award—SAP #4100072543, the Urban Health Collaborative at Drexel University , and the Built Environment and Health Research Group at Columbia University , Columbia University Robert N Butler Center for Aging, and a generous gift from Dana and David Dornsife to the Drexel University Dornsife School of Public Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health . Funding Information: Sara Godina is supported by NIH awards (5-T32-AG-55381-2 and 1R36AG076741-01) and the K. Leroy Irvis Fellowship at the University of Pittsburgh Graduate School of Public Health. Lilah Besser is supported by NIH/NIA award K01AG063895 and the Alzheimer's Association (AARG-21-850963). Jana Hirsch and Gina Lovasi are supported by the National Institute on Aging (1R01AG049970, 3R01AG049970-04S1), Commonwealth Universal Research Enhancement (C.U.R.E) program funded by the Pennsylvania Department of Health—2015 Formula award—SAP #4100072543, the Urban Health Collaborative at Drexel University, and the Built Environment and Health Research Group at Columbia University. Jana Hirsch is supported by National Institute on Aging (R01AG072634). Yvonne Michael is supported by National Institute on Aging (3R01AG049970-04S1). Jana Hirsch and Yvonne Michael are supported by the National Institute on Aging (1R01AG072634). The remaining authors have no funding to disclose.This work was supported by contracts HHSN268201200036C, HHSN268200800007C, HHSN268201800001C, N01HC55222, N01HC85079, N01HC85080, N01HC85081, N01HC85082, N01HC85083, N01HC85086, 75N92021D00006, and grants U01HL080295 and U01HL130114 from the National Heart, Lung, and Blood Institute (NHLBI), with additional contribution from the National Institute of Neurological Disorders and Stroke (NINDS). Additional support was provided by R01AG15928, R01AG20098, R01AG023629, and R01AG055404 from the National Institute on Aging (NIA). A full list of principal CHS investigators and institutions can be found at CHS-NHLBI.org. Incorporation of geographic characteristics was supported by the National Institute of Aging (grants 1R01AG049970, 3R01AG049970-04S1), Commonwealth Universal Research Enhancement (C.U.R.E) program funded by the Pennsylvania Department of Health—2015 Formula award—SAP #4100072543, the Urban Health Collaborative at Drexel University, and the Built Environment and Health Research Group at Columbia University, Columbia University Robert N Butler Center for Aging, and a generous gift from Dana and David Dornsife to the Drexel University Dornsife School of Public Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Funding Information: Sara Godina is supported by NIH awards ( 5-T32-AG-55381-2 and 1R36AG076741-01 ) and the K. Leroy Irvis Fellowship at the University of Pittsburgh Graduate School of Public Health. Lilah Besser is supported by NIH / NIA award K01AG063895 and the Alzheimer's Association (AARG-21-850963). Jana Hirsch and Gina Lovasi are supported by the National Institute on Aging ( 1R01AG049970 , 3R01AG049970-04S1 ), Commonwealth Universal Research Enhancement (C.U.R.E) program funded by the Pennsylvania Department of Health—2015 Formula award—SAP #4100072543, the Urban Health Collaborative at Drexel University , and the Built Environment and Health Research Group at Columbia University . Jana Hirsch is supported by National Institute on Aging ( R01AG072634 ). Yvonne Michael is supported by National Institute on Aging ( 3R01AG049970-04S1 ). Jana Hirsch and Yvonne Michael are supported by the National Institute on Aging ( 1R01AG072634 ). The remaining authors have no funding to disclose. Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",
year = "2023",
month = jan,
doi = "10.1016/j.healthplace.2022.102960",
language = "English (US)",
volume = "79",
journal = "Health and Place",
issn = "1353-8292",
publisher = "Elsevier Limited",
}