Abstract
Daniel Nathans (1928-99) pioneered the use of restriction endonucleases for the genetic analysis of cells and viruses. Focusing on the genome of simian virus 40, a small DNA tumor virus, Nathans developed many of the modern methods used to analyze DNA and set the stage for the recombinant DNA revolution. He shared the 1978 Nobel Prize in physiology or medicine with Hamilton O Smith and Werner Arber.
Original language | English (US) |
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Title of host publication | Brenner's Encyclopedia of Genetics |
Subtitle of host publication | Second Edition |
Publisher | Elsevier Inc. |
Pages | 6-7 |
Number of pages | 2 |
ISBN (Electronic) | 9780080961569 |
ISBN (Print) | 9780123749840 |
DOIs | |
State | Published - Feb 27 2013 |
Externally published | Yes |
Keywords
- Cleavage map
- Genetics
- Restriction endonucleases
- SV40
- Viruses
ASJC Scopus subject areas
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology
- General Medicine