Myxopapillary ependymoma: Cytomorphologic characteristics and differential diagnosis

Peter Kulesza, Tarik Tihan, Syed Z. Ali

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Myxopapillary ependymoma (ME) is a rare tumor with a predilection for sacrococcygeal area of adults. We present the cytomorphology of one such case in a 21-yr-old man, diagnosed by fine-needle aspiration (FNA). The tumor disclosed biphasic morphology with nests and aggregates of epithelioid malignant cells as well as branching cords of myxohyaline material. Most noticeable was the presence of distinct hyaline globules surrounded by neoplastic cells. The differential diagnosis of ME includes chordoma, adenoid cystic carcinoma, mucinous adenocarcinoma, and germ cell tumor. An accurate preoperative diagnosis of ME on FNA can be achieved based on its distinctive cytomorphologic features.

Original languageEnglish (US)
Pages (from-to)247-250
Number of pages4
JournalDiagnostic cytopathology
Issue number4
StatePublished - 2002


  • Cytomorphology
  • Fine-needle aspiration
  • Myxopapillary ependymoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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