Abstract
Myxoid tumors of soft tissue constitute a heterogeneous group of neoplasms characterized by the presence of a myxoid stromal matrix, which appears on H&E as an amorphous material and may be confused with edema. Superficial myxoid lesions in general are benign and deep ones are malignant. Grossly, they have a variable gelatinous quality and overlapping histologic features that may present diagnostic difficulties for pathologists. Most are sporadic neoplasms, with only a small percentage arising in patients with hereditary disorders. Discussed are key features of classic myxoid lesions, histologic features, characteristic clinical presentations, immunohistochemical patterns, cytogenetic analysis, and differential diagnosis.
Original language | English (US) |
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Pages (from-to) | 843-864 |
Number of pages | 22 |
Journal | Surgical Pathology Clinics |
Volume | 4 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2011 |
Externally published | Yes |
Keywords
- Benign lesions
- Cutaneous myxoma
- Intramuscular myxoma
- Malignant neoplasms
- Myxoid neoplasms
ASJC Scopus subject areas
- Surgery
- Pathology and Forensic Medicine