Myocardial energetics

L. E. Ford, Y. Kresh, E. Marban, S. Sideman

Research output: Contribution to journalArticlepeer-review


Inotropic alterations may alter contractile efficiency. Positive inotropic agents act mainly, if not exclusively, by increasing activation, which has very little effect on contractile efficiency. The metabolic effects of hypoxia may depress the contractile machinery directly. Acidosis is likely to decrease efficiency while an elevated phosphate, by itself, is likely to have little effect on efficiency.

Original languageEnglish (US)
Pages (from-to)39-49
Number of pages11
JournalAdvances in Experimental Medicine and Biology
StatePublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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