Myeloproliferative Neoplasms, Version 3.2022

Aaron T. Gerds; Jason Gotlib; Haris Ali; Prithviraj Bose; Andrew Dunbar; Amro Elshoury; Tracy I. George; Krishna Gundabolu; Elizabeth Hexner; Gabriela S. Hobbs; Tania Jain; Catriona Jamieson; Paul R. Kaesberg; Andrew T. Kuykendall; Yazan Madanat; Brandon McMahon; Sanjay R. Mohan; Kalyan V. Nadiminti; Stephen Oh; Animesh Pardanani; Nikolai Podoltsev; Lindsay Rein; Rachel Salit; Brady L. Stein; Moshe Talpaz; Pankit Vachhani; Martha Wadleigh; Sarah Wall; Dawn C. Ward; Mary Anne Bergman; Cindy Hochstetler

doi:10.6004/jnccn.2022.0046

Myeloproliferative Neoplasms, Version 3.2022

Aaron T. Gerds
, Jason Gotlib
, Haris Ali
, Prithviraj Bose
, Andrew Dunbar
, Amro Elshoury
, Tracy I. George
, Krishna Gundabolu
, Elizabeth Hexner
, Gabriela S. Hobbs
, Tania Jain
, Catriona Jamieson
, Paul R. Kaesberg
, Andrew T. Kuykendall
, Yazan Madanat
, Brandon McMahon
, Sanjay R. Mohan
, Kalyan V. Nadiminti
, Stephen Oh
, Animesh Pardanani

Nikolai Podoltsev, Lindsay Rein, Rachel Salit, Brady L. Stein, Moshe Talpaz, Pankit Vachhani, Martha Wadleigh, Sarah Wall, Dawn C. Ward, Mary Anne Bergman, Cindy Hochstetler

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

The classic Philadelphia chromosome-negativemyeloproliferative neoplasms (MPN) consist ofmyelofibrosis, polycythemia vera, and essential thrombocythemia and are a heterogeneous group of clonal blood disorders characterized by an overproduction of blood cells. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for MPN were developed as a result of meetings convened by a multidisciplinary panel with expertise in MPN, with the goal of providing recommendations for themanagement of MPN in adults. TheGuidelines include recommendations for the diagnostic workup, risk stratification, treatment, and supportive care strategies for the management of myelofibrosis, polycythemia vera, and essential thrombocythemia. Assessment of symptoms at baseline and monitoring of symptom status during the course of treatment is recommended for all patients. This article focuses on the recommendations as outlined in the NCCN Guidelines for the diagnosis of MPN and the risk stratification, management, and supportive care relevant to MF.

Original language	English (US)
Pages (from-to)	1033-1062
Number of pages	30
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	20
Issue number	9
DOIs	https://doi.org/10.6004/jnccn.2022.0046
State	Published - Sep 2022

ASJC Scopus subject areas

Oncology

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10.6004/jnccn.2022.0046

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Gerds, A. T., Gotlib, J., Ali, H., Bose, P., Dunbar, A., Elshoury, A., George, T. I., Gundabolu, K., Hexner, E., Hobbs, G. S., Jain, T., Jamieson, C., Kaesberg, P. R., Kuykendall, A. T., Madanat, Y., McMahon, B., Mohan, S. R., Nadiminti, K. V., Oh, S., ... Hochstetler, C. (2022). Myeloproliferative Neoplasms, Version 3.2022. JNCCN Journal of the National Comprehensive Cancer Network, 20(9), 1033-1062. https://doi.org/10.6004/jnccn.2022.0046

Gerds, AT, Gotlib, J, Ali, H, Bose, P, Dunbar, A, Elshoury, A, George, TI, Gundabolu, K, Hexner, E, Hobbs, GS, Jain, T, Jamieson, C, Kaesberg, PR, Kuykendall, AT, Madanat, Y, McMahon, B, Mohan, SR, Nadiminti, KV, Oh, S, Pardanani, A, Podoltsev, N, Rein, L, Salit, R, Stein, BL, Talpaz, M, Vachhani, P, Wadleigh, M, Wall, S, Ward, DC, Bergman, MA & Hochstetler, C 2022, 'Myeloproliferative Neoplasms, Version 3.2022', JNCCN Journal of the National Comprehensive Cancer Network, vol. 20, no. 9, pp. 1033-1062. https://doi.org/10.6004/jnccn.2022.0046

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title = "Myeloproliferative Neoplasms, Version 3.2022",

abstract = "The classic Philadelphia chromosome-negativemyeloproliferative neoplasms (MPN) consist ofmyelofibrosis, polycythemia vera, and essential thrombocythemia and are a heterogeneous group of clonal blood disorders characterized by an overproduction of blood cells. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for MPN were developed as a result of meetings convened by a multidisciplinary panel with expertise in MPN, with the goal of providing recommendations for themanagement of MPN in adults. TheGuidelines include recommendations for the diagnostic workup, risk stratification, treatment, and supportive care strategies for the management of myelofibrosis, polycythemia vera, and essential thrombocythemia. Assessment of symptoms at baseline and monitoring of symptom status during the course of treatment is recommended for all patients. This article focuses on the recommendations as outlined in the NCCN Guidelines for the diagnosis of MPN and the risk stratification, management, and supportive care relevant to MF.",

author = "Gerds, \{Aaron T.\} and Jason Gotlib and Haris Ali and Prithviraj Bose and Andrew Dunbar and Amro Elshoury and George, \{Tracy I.\} and Krishna Gundabolu and Elizabeth Hexner and Hobbs, \{Gabriela S.\} and Tania Jain and Catriona Jamieson and Kaesberg, \{Paul R.\} and Kuykendall, \{Andrew T.\} and Yazan Madanat and Brandon McMahon and Mohan, \{Sanjay R.\} and Nadiminti, \{Kalyan V.\} and Stephen Oh and Animesh Pardanani and Nikolai Podoltsev and Lindsay Rein and Rachel Salit and Stein, \{Brady L.\} and Moshe Talpaz and Pankit Vachhani and Martha Wadleigh and Sarah Wall and Ward, \{Dawn C.\} and Bergman, \{Mary Anne\} and Cindy Hochstetler",

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doi = "10.6004/jnccn.2022.0046",

language = "English (US)",

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AU - Ali, Haris

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AU - Elshoury, Amro

AU - George, Tracy I.

AU - Gundabolu, Krishna

AU - Hexner, Elizabeth

AU - Hobbs, Gabriela S.

AU - Jain, Tania

AU - Jamieson, Catriona

AU - Kaesberg, Paul R.

AU - Kuykendall, Andrew T.

AU - Madanat, Yazan

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AU - Oh, Stephen

AU - Pardanani, Animesh

AU - Podoltsev, Nikolai

AU - Rein, Lindsay

AU - Salit, Rachel

AU - Stein, Brady L.

AU - Talpaz, Moshe

AU - Vachhani, Pankit

AU - Wadleigh, Martha

AU - Wall, Sarah

AU - Ward, Dawn C.

AU - Bergman, Mary Anne

AU - Hochstetler, Cindy

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Myeloproliferative Neoplasms, Version 3.2022

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