Myeloma Neuropathy: Successful Treatment of Two Patients and Review of Cases

Larry E. Davis, Daniel B. Drachman

Research output: Contribution to journalArticlepeer-review

68 Scopus citations


Two patients with occult solitary myeloma had a progressive, painful sensorimotor peripheral neuropathy that improved after localized radiotherapy to the myeloma site. The patients have had remissions of the neuropathy and myeloma for 10 and 11/2 years. Review of 46 cases of myeloma and neuropathy indicates that a progressive, painful sensorimotor neuropathy in a middle-aged man suggests a myeloma neuropathy. The neuropathy preceded detection of the myeloma in 80% of the cases. The myeloma was solitary 24% of the time. Radiotherapy, particularly to a solitary myeloma, offered the greatest chance for remission of the neuropathy.

Original languageEnglish (US)
Pages (from-to)507-511
Number of pages5
JournalArchives of neurology
Issue number6
StatePublished - Dec 1972

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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