Abstract
Myelin in the central nervous system of 19-day-old Snell’s dwarf mice was studied morphologically and biochemically. The number of myelinated axons per unit area in the corticospinal tract and anterior commissure of dwarf mice was significantly decreased. The distribution of myelinated fibers based upon sheath thickness was normal. The yield of isolated myelin was decreased by 56% in the dwarf but its composition of lipids, proteins, glycoproteins and 2’,3’-cyclic nucleotide 3’-phosphohydrolase activity was nearly equivalent to that of control myelin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 465-477 |
| Number of pages | 13 |
| Journal | Journal of Neuropathology and Experimental Neurology |
| Volume | 34 |
| Issue number | 6 |
| State | Published - 1975 |
ASJC Scopus subject areas
- Clinical Neurology
- Pathology and Forensic Medicine
- Cellular and Molecular Neuroscience
- Neurology
- Neuroscience(all)