MUSSEL: Enhanced Bayesian polygenic risk prediction leveraging information across multiple ancestry groups

Keyphrases

• Polygenic Risk Score 100%
• Polygenic Risk Prediction 100%
• Genome-wide Association Study 66%
• Linkage Disequilibrium 33%
• Complex Traits 33%
• Diverse Populations 33%
• African Ancestry 33%
• Simulation Study 33%
• Bayesian Hierarchical Model 33%
• Complex Disease 33%
• Performance Prediction 33%
• Combined Method 33%
• Simulation Data 33%
• Complex Varieties 33%
• Polygenic Prediction 33%
• Average Gain 33%
• Borrowing Information 33%
• Continuous Traits 33%
• Performance Gap 33%
• Ancestry-specific 33%
• Modelling Learning 33%
• Trait Linkage 33%
• Trait Structure 33%
• Ancestral Diversity 33%
• Ensemble Learning 33%
• Hierarchical Ensembles 33%

Biochemistry, Genetics and Molecular Biology

• Genome-Wide Association Study 100%
• Gene Linkage Disequilibrium 50%
• Sample Size 50%

Neuroscience

• Genome-Wide Association Study 100%
• Linkage Disequilibrium 50%