Murine models of polycystic kidney disease

Luis Fernando Menezes, Gregory George Germino

Research output: Contribution to journalArticlepeer-review


Polycystic diseases affect approximately 1/1000 and are important causes of kidney failure. No therapies presently are in clinical practice that can prevent disease progression. Multiple mouse models have been produced for the genetic forms of the disease that most commonly affect humans. In this report, we review recent progress in the field and describe some of the outstanding challenges.

Original languageEnglish (US)
JournalDrug Discovery Today: Disease Mechanisms
StateAccepted/In press - 2013
Externally publishedYes

ASJC Scopus subject areas

  • Drug Discovery
  • Molecular Medicine


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