Mumps vaccine effectiveness in highly immunized populations

Angela Domínguez; Núria Torner; Jesús Castilla; Joan Batalla; Pere Godoy; Marcela Guevara; Dolors Carnicer; Joan Caylà; Cristina Rius; Josep Maria Jansà

doi:10.1016/j.vaccine.2010.02.107

Mumps vaccine effectiveness in highly immunized populations

Angela Domínguez, Núria Torner, Jesús Castilla, Joan Batalla, Pere Godoy, Marcela Guevara, Dolors Carnicer, Joan Caylà, Cristina Rius, Josep Maria Jansà

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks.

Original language	English (US)
Pages (from-to)	3567-3570
Number of pages	4
Journal	Vaccine
Volume	28
Issue number	20
DOIs	https://doi.org/10.1016/j.vaccine.2010.02.107
State	Published - Apr 30 2010
Externally published	Yes

Keywords

Immunization
Mumps
Vaccine effectiveness

ASJC Scopus subject areas

Molecular Medicine
General Immunology and Microbiology
General Veterinary
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1016/j.vaccine.2010.02.107

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title = "Mumps vaccine effectiveness in highly immunized populations",

abstract = "The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks.",

keywords = "Immunization, Mumps, Vaccine effectiveness",

author = "Angela Dom{\'i}nguez and N{\'u}ria Torner and Jes{\'u}s Castilla and Joan Batalla and Pere Godoy and Marcela Guevara and Dolors Carnicer and Joan Cayl{\`a} and Cristina Rius and Jans{\`a}, {Josep Maria}",

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AU - Domínguez, Angela

AU - Torner, Núria

AU - Castilla, Jesús

AU - Batalla, Joan

AU - Godoy, Pere

AU - Guevara, Marcela

AU - Carnicer, Dolors

AU - Caylà, Joan

AU - Rius, Cristina

AU - Jansà, Josep Maria

PY - 2010/4/30

Y1 - 2010/4/30

N2 - The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks.

AB - The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks.

KW - Immunization

KW - Mumps

KW - Vaccine effectiveness

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Mumps vaccine effectiveness in highly immunized populations

Abstract

Keywords

ASJC Scopus subject areas

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