Abstract
We introduce sequential testing procedures for the planning and analysis of reliability studies to assess an exposure's measurement error. The designs allow repeated evaluation of reliability of the measurements and stop testing if early evidence shows the measurement error is within the level of tolerance. Methods are developed and critical values tabulated for a number of two-stage designs. The methods are exemplified using an example evaluating the reliability of biomarkers associated with oxidative stress.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1190-1196 |
| Number of pages | 7 |
| Journal | Biometrics |
| Volume | 62 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 2006 |
| Externally published | Yes |
Keywords
- Interim analysis
- Intraclass correlation
- Measurement error
- Power and sample size
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Applied Mathematics
- Biochemistry, Genetics and Molecular Biology(all)
- Immunology and Microbiology(all)
- Statistics and Probability