Multisection proton MR spectroscopic imaging of the brain

J. H. Duyn, J. Gillen, G. Sobering, P. C.M. Van Zijl, C. T.W. Moonen

Research output: Contribution to journalArticlepeer-review

314 Scopus citations


The authors developed a hydrogen-1 proton magnetic resonance (MR) imaging method in which metabolic information is acquired by obtaining multiple sections through the brain. A spin-echo sequence is used for section selection, an octangular outer volume saturation pulse for lipid suppression, and a chemical-shift-selective saturation pulse for water suppression. High- quality maps of choline, creatine, and N-acetylaspartate were obtained in six studies performed in four volunteers. Water and lipid signal from the skull area was well suppressed by the pulse sequence used.

Original languageEnglish (US)
Pages (from-to)277-282
Number of pages6
Issue number1
StatePublished - Jan 1 1993
Externally publishedYes


  • Brain, MR
  • Magnetic resonance (MR), spectroscopy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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