Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: Carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged

Kathleen A. Smith, Olga B. Chernova, Richard P. Groves, Mary B. Stark, José L. Martínez, Jeffrey N. Davidson, Jeffrey M. Trent, Thomas E. Patterson, Archana Agarwal, Pamela Duncan, Munna L. Agarwal, George R. Stark

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Biochemistry, Genetics and Molecular Biology

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