Multi-subject atlas built from structural tongue magnetic resonance images

Jonghye Woo, Junghoon Lee, John Bogovic, Emi Z Murano, Fangxu Xing, Maureen Stone, Jerry L. Prince

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations


Magnetic resonance imaging (MRI) is a widely used technology for non-invasive tongue imaging. MRI can detail tongue and muscle shapes and their variability in both healthy and diseased populations. Such detail can aid significantly in the interpretation of muscle interactions in the tongue for both normal and disordered speech production. However, the size or shape of the tongue and muscles may vary from one subject to another. In addition, there exists no comprehensive and systematic framework to assess the difference and variability of tongue and muscles in a normalized space. In the present work, we built a multi-subject atlas from 20 normal subjects that are acquired using structural MRI to offer a normalized space on which all subjects from a target population can be mapped and compared. In order to find accurate one-to-one correspondences, we bounded the tongue so that each volume had the same vocal tract features. For registration, we used symmetric diffeomorphic image registration with a cross-correlation similarity metric, which is widely used in brain image analysis. The atlas facilitates a template-based segmentation in assigning anatomical labels in the images. The tongue atlas is unprecedented and opens new vistas for exploring normal and diseased oral structures and function.

Original languageEnglish (US)
Article number060194
JournalProceedings of Meetings on Acoustics
StatePublished - 2013
Event21st International Congress on Acoustics, ICA 2013 - 165th Meeting of the Acoustical Society of America - Montreal, QC, Canada
Duration: Jun 2 2013Jun 7 2013

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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