Multi-modality Neuro-Monitoring: Conventional Clinical Trial Design

Alexandros L. Georgiadis, Yuko Y. Palesch, David Zygun, J. Claude Hemphill, Claudia S. Robertson, Peter D. Leroux, Jose I. Suarez

Research output: Contribution to journalArticlepeer-review


Multi-modal monitoring has become an integral part of neurointensive care. However, our approach is at this time neither standardized nor backed by data from randomized controlled trials. The goal of the second Neurocritical Care Research Conference was to discuss research priorities in multi-modal monitoring, what research tools are available, as well as the latest advances in clinical trial design. This section of the meeting was focused on how such a trial should be designed so as to maximize yield and avoid mistakes of the past.

Original languageEnglish (US)
Pages (from-to)369-377
Number of pages9
JournalNeurocritical care
Issue number3
StatePublished - Jun 1 2015
Externally publishedYes


  • Intracranial pressure
  • Multi-modal monitoring
  • Neurocritical care
  • Randomized controlled trials

ASJC Scopus subject areas

  • Clinical Neurology
  • Critical Care and Intensive Care Medicine


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