Multi-gram scale synthesis of FR180204

Samarjit Patnaik; Harry C. Dietz; Wei Zheng; Christopher Austin; Juan J. Marugan

doi:10.1021/jo901835m

Multi-gram scale synthesis of FR180204

Samarjit Patnaik, Harry C. Dietz, Wei Zheng, Christopher Austin, Juan J. Marugan

Johns Hopkins Hospital

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

(Chemical Equation Presented) A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204.

Original language	English (US)
Pages (from-to)	8870-8873
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	74
Issue number	22
DOIs	https://doi.org/10.1021/jo901835m
State	Published - Nov 20 2009

ASJC Scopus subject areas

Organic Chemistry

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10.1021/jo901835m

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title = "Multi-gram scale synthesis of FR180204",

abstract = "(Chemical Equation Presented) A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204.",

author = "Samarjit Patnaik and Dietz, {Harry C.} and Wei Zheng and Christopher Austin and Marugan, {Juan J.}",

year = "2009",

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T1 - Multi-gram scale synthesis of FR180204

AU - Patnaik, Samarjit

AU - Dietz, Harry C.

AU - Zheng, Wei

AU - Austin, Christopher

AU - Marugan, Juan J.

PY - 2009/11/20

Y1 - 2009/11/20

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AB - (Chemical Equation Presented) A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204.

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EP - 8873

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 22

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Multi-gram scale synthesis of FR180204

Abstract

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