Abstract
LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 534-535 |
| Number of pages | 2 |
| Journal | Cell |
| Volume | 163 |
| Issue number | 3 |
| DOIs | |
| State | Published - Oct 22 2015 |
| Externally published | Yes |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology
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