MRI of CEST-Based Reporter Gene

Guanshu Liu; Assaf A. Gilad

doi:10.1007/978-1-61779-219-9_36

MRI of CEST-Based Reporter Gene

Guanshu Liu, Assaf A. Gilad

Kennedy Krieger Institute

Research output: Chapter in Book/Report/Conference proceeding › Chapter

6 Scopus citations

Abstract

In recent years, several reporter genes have been designed for non-invasive magnetic resonance imaging (MRI). Here, we offer a brief summary of recent advances in MRI reporter gene technology, as well as elaborated protocols for cloning, expression, and imaging of reporter genes based on a chemical exchange saturation transfer (CEST) method. These protocols emphasize new developments in CEST-MRI data acquisition and processing.

Original language	English (US)
Title of host publication	In vivo NMR Imaging
Subtitle of host publication	Methods and Protocols
Publisher	Humana Press Inc.
Pages	733-746
Number of pages	14
ISBN (Print)	9781617792182
DOIs	https://doi.org/10.1007/978-1-61779-219-9_36
State	Published - 2011

Publication series

Name	Methods in Molecular Biology
Volume	771
ISSN (Print)	1064-3745
ISSN (Electronic)	1940-6029

Keywords

CEST
MRI
MRI reporter gene
in vivo MR imaging
molecular imaging

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-61779-219-9_36

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abstract = "In recent years, several reporter genes have been designed for non-invasive magnetic resonance imaging (MRI). Here, we offer a brief summary of recent advances in MRI reporter gene technology, as well as elaborated protocols for cloning, expression, and imaging of reporter genes based on a chemical exchange saturation transfer (CEST) method. These protocols emphasize new developments in CEST-MRI data acquisition and processing.",

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author = "Guanshu Liu and Gilad, {Assaf A.}",

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AB - In recent years, several reporter genes have been designed for non-invasive magnetic resonance imaging (MRI). Here, we offer a brief summary of recent advances in MRI reporter gene technology, as well as elaborated protocols for cloning, expression, and imaging of reporter genes based on a chemical exchange saturation transfer (CEST) method. These protocols emphasize new developments in CEST-MRI data acquisition and processing.

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KW - MRI

KW - MRI reporter gene

KW - in vivo MR imaging

KW - molecular imaging

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MRI of CEST-Based Reporter Gene

Abstract

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Keywords

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