MR-guided radiofrequency ablation in a 0.2-T open MR system: Technical success and technique effectiveness in 100 liver tumors

Stephan Clasen, Andreas Boss, Diethard Schmidt, Christina Schraml, Jan Fritz, Fritz Schick, Claus D. Claussen, Philippe L. Pereira

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Purpose: To evaluate the feasibility and technique effectiveness of magnetic resonance (MR)-guided radiofrequency (RF) ablation of hepatic malignancies. Materials and Methods: In 64 patients, 100 primary (N = 19) or secondary (N = 81) liver tumors (mean diameter = 24.7 mm; range = 4-60 mm) were treated with 87 sessions of MR-guided RF ablation. The entire ablation procedure was carried out at an 0.2-T open MR system by using MR-compatible internally cooled electrodes. T2-weighted turbo spin echo sequences (TR/TE = 3500 msec/110 msec) were used to monitor thermally induced coagulation. Technique effectiveness was assessed four months after the last RF ablation by dynamic MR imaging at 1.5-T. Results: MR-guided RF ablation procedures were technical successful in 85 of 87 (97.7%) assessed at the end of each session. Complete coagulation was intended in 99 of 100 tumors. Technique effectiveness was observed in 92 of 99 (92.9%) of these tumors. To achieve complete coagulation 82 of 92 (89.1%) tumors required a single session. T2-weighted sequences were accurate to monitor the extent of coagulation and were supportive to guide overlapping ablation. There were two of 87 (2.3%) major and seven of 87 (8.0%) minor complications. Conclusion: MR-guided RF ablation is a safe and effective therapy in the treatment of hepatic malignancies. MR imaging offers an accurate monitoring of thermally-induced coagulation, thus enabling complete tumor coagulation in a single session.

Original languageEnglish (US)
Pages (from-to)1043-1052
Number of pages10
JournalJournal of Magnetic Resonance Imaging
Issue number4
StatePublished - Oct 2007
Externally publishedYes


  • Hepatocellular carcinoma
  • Interventional MRI
  • Liver
  • MR imaging
  • Metastases
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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