Moving forward: Mechanisms of chemoattractant gradient sensing

Jonathan Franca-Koh; Peter N. Devreotes

doi:10.1152/physiol.00017.2004

Moving forward: Mechanisms of chemoattractant gradient sensing

Jonathan Franca-Koh, Peter N. Devreotes

School of Medicine

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

Cells use an internal compass to sense the direction of chemoattractant gradients. This is used to bias pseudopod extension at the front of the cell and to orient cell polarization. Recent studies have highlighted the important roles played by phosphoinositide-3,4,5-triphosphate and small G proteins, but many questions remain.

Original language	English (US)
Pages (from-to)	300-308
Number of pages	9
Journal	Physiology
Volume	19
Issue number	5
DOIs	https://doi.org/10.1152/physiol.00017.2004
State	Published - Oct 2004

ASJC Scopus subject areas

Physiology

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title = "Moving forward: Mechanisms of chemoattractant gradient sensing",

abstract = "Cells use an internal compass to sense the direction of chemoattractant gradients. This is used to bias pseudopod extension at the front of the cell and to orient cell polarization. Recent studies have highlighted the important roles played by phosphoinositide-3,4,5-triphosphate and small G proteins, but many questions remain.",

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AB - Cells use an internal compass to sense the direction of chemoattractant gradients. This is used to bias pseudopod extension at the front of the cell and to orient cell polarization. Recent studies have highlighted the important roles played by phosphoinositide-3,4,5-triphosphate and small G proteins, but many questions remain.

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Moving forward: Mechanisms of chemoattractant gradient sensing

Abstract

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