Monkey nucleus basalis is enriched with choline acetyltransferase

M. McKinney, R. G. Struble, D. L. Price, J. T. Coyle

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


The nucleus basalis of Meynert, which projects directly and diffusely to the cerebral cortex, was histologically identified in Nissl- and acetylcholinesterase-stained sections of the forebrain of Rhesus monkeys. Adjacent 1 mm thick sections were microdissected in 2 mm2 blocks and assayed for choline acetyltransferase activity. The results demonstrate a marked enrichment of choline acetyltransferase activity in samples containing the nucleus basalis of Meynert and strongly suggest that this nucleus is a cholinergic nucleus in the primate.

Original languageEnglish (US)
Pages (from-to)2363-2368
Number of pages6
Issue number10
StatePublished - Oct 1982
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)


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