Monitoring methylmercury during pregnancy: Maternal hair predicts fetal brain exposure

E. Cernichiari; R. Brewer; G. J. Myers; D. O. Marsh; L. W. Lapham; C. Cox; C. F. Shamlaye; M. Berlin; P. W. Davidson; T. W. Clarkson

Monitoring methylmercury during pregnancy: Maternal hair predicts fetal brain exposure

E. Cernichiari, R. Brewer, G. J. Myers, D. O. Marsh, L. W. Lapham, C. Cox, C. F. Shamlaye, M. Berlin, P. W. Davidson, T. W. Clarkson

Research output: Contribution to journal › Article › peer-review

192 Scopus citations

Abstract

Autopsy brains were obtained from infants dying from a variety of causes within a few days of birth in a population exposed to methylmercury in fish. Infant and maternal blood and hair samples were also obtained. The concentration of total mercury in 6 major brain regions were highly correlated with maternal hair levels. This correlation was confirmed by a sequence of comparisons of maternal hair to maternal blood to infant blood and finally to infant brain. The results lend support to the use of maternal hair in assessing fetal exposure to methylmercury in fish-eating populations.

Original language	English (US)
Pages (from-to)	705-709
Number of pages	5
Journal	NeuroToxicology
Volume	16
Issue number	4
State	Published - 1995
Externally published	Yes

Keywords

fetal brain
maternal hair
methylmercury

ASJC Scopus subject areas

General Neuroscience
Toxicology

Cite this

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title = "Monitoring methylmercury during pregnancy: Maternal hair predicts fetal brain exposure",

abstract = "Autopsy brains were obtained from infants dying from a variety of causes within a few days of birth in a population exposed to methylmercury in fish. Infant and maternal blood and hair samples were also obtained. The concentration of total mercury in 6 major brain regions were highly correlated with maternal hair levels. This correlation was confirmed by a sequence of comparisons of maternal hair to maternal blood to infant blood and finally to infant brain. The results lend support to the use of maternal hair in assessing fetal exposure to methylmercury in fish-eating populations.",

keywords = "fetal brain, maternal hair, methylmercury",

author = "E. Cernichiari and R. Brewer and Myers, {G. J.} and Marsh, {D. O.} and Lapham, {L. W.} and C. Cox and Shamlaye, {C. F.} and M. Berlin and Davidson, {P. W.} and Clarkson, {T. W.}",

year = "1995",

language = "English (US)",

volume = "16",

pages = "705--709",

journal = "NeuroToxicology",

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TY - JOUR

T1 - Monitoring methylmercury during pregnancy

T2 - Maternal hair predicts fetal brain exposure

AU - Cernichiari, E.

AU - Brewer, R.

AU - Myers, G. J.

AU - Marsh, D. O.

AU - Lapham, L. W.

AU - Cox, C.

AU - Shamlaye, C. F.

AU - Berlin, M.

AU - Davidson, P. W.

AU - Clarkson, T. W.

PY - 1995

Y1 - 1995

N2 - Autopsy brains were obtained from infants dying from a variety of causes within a few days of birth in a population exposed to methylmercury in fish. Infant and maternal blood and hair samples were also obtained. The concentration of total mercury in 6 major brain regions were highly correlated with maternal hair levels. This correlation was confirmed by a sequence of comparisons of maternal hair to maternal blood to infant blood and finally to infant brain. The results lend support to the use of maternal hair in assessing fetal exposure to methylmercury in fish-eating populations.

AB - Autopsy brains were obtained from infants dying from a variety of causes within a few days of birth in a population exposed to methylmercury in fish. Infant and maternal blood and hair samples were also obtained. The concentration of total mercury in 6 major brain regions were highly correlated with maternal hair levels. This correlation was confirmed by a sequence of comparisons of maternal hair to maternal blood to infant blood and finally to infant brain. The results lend support to the use of maternal hair in assessing fetal exposure to methylmercury in fish-eating populations.

KW - fetal brain

KW - maternal hair

KW - methylmercury

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SN - 0161-813X

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JO - NeuroToxicology

JF - NeuroToxicology

IS - 4

ER -

Monitoring methylmercury during pregnancy: Maternal hair predicts fetal brain exposure

Abstract

Keywords

ASJC Scopus subject areas

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