@article{934d7fa948684d2caa3cbe5b35b5decc,
title = "Molecular techniques and genetic alterations in head and neck cancer",
abstract = "It is well known that cellular DNA alterations can lead to the formation of cancer, and there has been much discovery in the pathways involved in the development of head and neck squamous cell carcinoma (HNSCC). With novel genome-wide molecular assays, our ability to detect these abnormalities has increased. We now have a better understanding of the molecular complexity of HNSCC, but there is still much research to be done. In this review, we discuss the well described genetic alterations and touch on the newer findings, as well as some of the future directions of head and neck cancer research.",
keywords = "DNA, Head and neck cancer, Molecular, Oral cancer",
author = "Ha, {Patrick K.} and Chang, {Steven S.} and Glazer, {Chad A.} and Califano, {Joseph A.} and David Sidransky",
note = "Funding Information: Dr. Califano is supported by a Clinical Innovator Award from the Flight Attendant Medical Research Institute, the National Institute of Dental and Craniofacial Research (1R01DE015939-01), and the National Cancer Institute SPORE (5P50CA096784-05). Dr. Glazer is supported, in part, by the NIH training Grant No. T32DC00027. Funding Information: Dr. Sidransky is supported by the NCI 5P01CA077664-09 and 5U01CA084986-09 NIDCR 9P50DE019032-06, 5R01DE013561-07, and 5R37DE012588-10. Funding Information: Dr. Ha is supported by the National Institute of Dental and Craniofacial Research (5K08DE018463-02), the Johns Hopkins Clinician Scientist Award, and the National Cancer Institute SPORE (5P50CA096784-05). ",
year = "2009",
month = apr,
doi = "10.1016/j.oraloncology.2008.05.015",
language = "English (US)",
volume = "45",
pages = "335--339",
journal = "Oral Oncology",
issn = "1368-8375",
publisher = "Elsevier Limited",
number = "4-5",
}