Molecular neurobiological methods in marijuana-cannabinoid research.

George R. Uhl, Hiroki Ishiguro, Emmanuel S. Onaivi, Ping Wu Zhang, B. Emmanuel Akinshola, Zhicheng Lin, Bruce Hope, Claire M. Leonard, Qing Rong Liu

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

Recent aggregation of evidence for the roles of endogenous agonist and receptor systems that are mimicked or activated by cannabanoid ligands has provided a focus for work that has elucidated details of some of the multiple physiological roles and pharmacological functions that these systems play in brain and peripheral tissues. This chapter reviews some of the approaches to improved elucidation of these systems, with special focus on the human genes that encode cannabanoid receptors and the variants in these receptors that appear likely to contribute to human addiction vulnerabilities.

Original languageEnglish (US)
Pages (from-to)1-17
Number of pages17
JournalMethods in Molecular Medicine
Volume123
StatePublished - 2006
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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