Molecular genetics of exocrine pancreatic neoplasms

S. A. Hahn, S. E. Kern

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


Molecular genetic studies of pancreatic ductal adenocarcinoma have revealed the common co-existence of K-ras, p53, and MTS1 mutations. The finding of K-ras mutations in epithelial lesions of ducts suggests them as a precursor intraepithelial neoplasm. The clinical importance of this line of work can only be anticipated at present, and a fuller understanding of genetic alterations in these neoplasms is necessary.

Original languageEnglish (US)
Pages (from-to)857-869
Number of pages13
JournalSurgical Clinics of North America
Issue number5
StatePublished - 1995

ASJC Scopus subject areas

  • Surgery


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