Abstract
Defects in mismatch repair genes cause the genetic instability characteristic of hereditary nonpolyposis colorectal cancer and a subset of sporadic colon tumors. The newest member of the mismatch repair gene family, GTBP, has recently been identified as a partial cDNA. Here, we describe the isolation of its 5' terminus, allowing definition of the entire coding region. Several polymorphisms within the 5' end were identified and are presented.
Original language | English (US) |
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Pages (from-to) | 395-397 |
Number of pages | 3 |
Journal | Genomics |
Volume | 31 |
Issue number | 3 |
DOIs | |
State | Published - Feb 1 1996 |
ASJC Scopus subject areas
- Genetics