MOG antibody–associated encephalomyelitis/encephalitis

Sara Salama; Majid Khan; Santiago Pardo; Izlem Izbudak; Michael Levy

doi:10.1177/1352458519837705

MOG antibody–associated encephalomyelitis/encephalitis

Sara Salama, Majid Khan, Santiago Pardo, Izlem Izbudak, Michael Levy

School of Medicine

Research output: Contribution to journal › Review article › peer-review

24 Scopus citations

Abstract

Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM). In this review, we discuss MOG-positive cases presenting with encephalitis, encephalopathy, or ADEM-like presentation based on recently published series.

Original language	English (US)
Pages (from-to)	1427-1433
Number of pages	7
Journal	Multiple Sclerosis Journal
Volume	25
Issue number	11
DOIs	https://doi.org/10.1177/1352458519837705
State	Published - Oct 1 2019

Keywords

MOG antibody disease
MOG encephalomyelitis
MOG-EM
anti-MOG
myelin oligodendrocyte glycoprotein
optic neuritis
transverse myelitis

ASJC Scopus subject areas

Neurology
Clinical Neurology

Access to Document

10.1177/1352458519837705

Cite this

@article{1548998a311147cfa4ac435d763d1e53,

title = "MOG antibody–associated encephalomyelitis/encephalitis",

abstract = "Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM). In this review, we discuss MOG-positive cases presenting with encephalitis, encephalopathy, or ADEM-like presentation based on recently published series.",

keywords = "MOG antibody disease, MOG encephalomyelitis, MOG-EM, anti-MOG, myelin oligodendrocyte glycoprotein, optic neuritis, transverse myelitis",

author = "Sara Salama and Majid Khan and Santiago Pardo and Izlem Izbudak and Michael Levy",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was funded by an R01 grant from the National Institute of Allergy and Infectious Diseases (grant no.: AI130548) through M.L. and a grant from the Egyptian Ministry of Higher Education (grant no.: JS-3725, SS). Publisher Copyright: {\textcopyright} The Author(s), 2019.",

year = "2019",

month = oct,

day = "1",

doi = "10.1177/1352458519837705",

language = "English (US)",

volume = "25",

pages = "1427--1433",

journal = "Multiple Sclerosis Journal",

issn = "1352-4585",

publisher = "SAGE Publications Ltd",

number = "11",

}

TY - JOUR

T1 - MOG antibody–associated encephalomyelitis/encephalitis

AU - Salama, Sara

AU - Khan, Majid

AU - Pardo, Santiago

AU - Izbudak, Izlem

AU - Levy, Michael

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was funded by an R01 grant from the National Institute of Allergy and Infectious Diseases (grant no.: AI130548) through M.L. and a grant from the Egyptian Ministry of Higher Education (grant no.: JS-3725, SS). Publisher Copyright: © The Author(s), 2019.

PY - 2019/10/1

Y1 - 2019/10/1

N2 - Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM). In this review, we discuss MOG-positive cases presenting with encephalitis, encephalopathy, or ADEM-like presentation based on recently published series.

AB - Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM). In this review, we discuss MOG-positive cases presenting with encephalitis, encephalopathy, or ADEM-like presentation based on recently published series.

KW - MOG antibody disease

KW - MOG encephalomyelitis

KW - MOG-EM

KW - anti-MOG

KW - myelin oligodendrocyte glycoprotein

KW - optic neuritis

KW - transverse myelitis

UR - http://www.scopus.com/inward/record.url?scp=85063580054&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85063580054&partnerID=8YFLogxK

U2 - 10.1177/1352458519837705

DO - 10.1177/1352458519837705

M3 - Review article

C2 - 30907249

AN - SCOPUS:85063580054

SN - 1352-4585

VL - 25

SP - 1427

EP - 1433

JO - Multiple Sclerosis Journal

JF - Multiple Sclerosis Journal

IS - 11

ER -

MOG antibody–associated encephalomyelitis/encephalitis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this