MOG Antibody-Associated Disease and Thymic Hyperplasia: From the National Multiple Sclerosis Society Case Conference Proceedings

Brigitte Hurtubise, Elliot M. Frohman, Steven Galetta, Laura J. Balcer, Teresa C. Frohman, Robert P. Lisak, Scott D. Newsome, Jennifer S. Graves, Scott S. Zamvil, Lilyana Amezcua

Research output: Contribution to journalArticlepeer-review

Abstract

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently described CNS inflammatory disorder that may manifest with optic neuritis, myelitis, seizures, and/or acute disseminated encephalomyelitis. While MOG-specific antibodies in patients with MOGAD are IgG1, a T-cell-dependent antibody isotype, immunologic mechanisms of this disease are not fully understood. Thymic hyperplasia can be associated with certain autoimmune diseases. In this report we describe a case of MOGAD associated with thymic hyperplasia in a young adult.

Original languageEnglish (US)
Article numbere200077
JournalNeurology: Neuroimmunology and NeuroInflammation
Volume10
Issue number2
DOIs
StatePublished - Mar 14 2023

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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