@article{85f4dae32b67474c964f63f824b88e34,
title = "Modeling environmental influences on child growth in the MAL-ED cohort study: Opportunities and challenges",
abstract = "Although genetics, maternal undernutrition and low birth weight status certainly play a role in child growth, dietary insufficiency and infectious diseases are key risk factors for linear growth faltering during early childhood. A primary goal of the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is to identify specific risk factors associated with growth faltering during the first 2 years of life; however, growth in early childhood is challenging to characterize because growth may be inherently nonlinear with age. In this manuscript, we describe some methods for analyzing longitudinal growth to evaluate both short-and long-term associations between risk factors and growth trajectories over the first 2 years of life across 8 resource-limited settings using harmonized protocols. We expect there will be enough variability within and between sites in the prevalence of risk factors and burden of linear growth faltering to allow us to distinguish some of the key pathways to linear growth faltering in the MAL-ED study.",
keywords = "MAL-ED, diarrhea, growth, malnutrition, stunting",
author = "{MAL-ED Network Investigators} and Richard, {Stephanie A.} and McCormick, {Benjamin J.J.} and Miller, {Mark A.} and Caulfield, {Laura E.} and William Checkley and Acosta, {A. M.} and Chavez, {C. B.} and Flores, {J. T.} and Olotegui, {M. P.} and Pinedo, {S. R.} and Trigoso, {D. R.} and Vasquez, {A. O.} and I. Ahmed and D. Alam and A. Ali and Bhutta, {Z. A.} and S. Qureshi and S. Shakoor' and S. Soofi and A. Turab and Yousafzai, {A. K.} and Zaidi, {A. K.} and L. Bodhidatta and Mason, {C. J.} and S. Babji and A. Bose and S. John and G. Kang and B. Kurien and J. Muliyil and Raghava, {M. V.} and A. Ramachandran and A. Rose and W. Pan and R. Ambikapathi and D. Carreon and V. Charu and L. Dabo and V. Doan and J. Graham and C. Hoest and S. Knobler and D. Lang and M. McGrath and A. Mohale and R. Black and P. Chen and M. Kosek and G. Lee and Yori, {P. P.}",
note = "Funding Information: Financial support. The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development Project (MAL-ED) is carried out as a collaborative project supported by the Bill & Melinda Gates Foundation, the Foundation for the National Institutes of Health, and the National Institutes of Health, Fogarty International Center. M. M. was supported by the National Institutes of Health, Fogarty International Center. Funding Information: Supplement sponsorship. This article appeared as part of the supplement “The Malnutrition and Enteric Disease Study (MAL-ED): Understanding the Consequences for Child Health and Development,” sponsored by the National Institutes of Health and the Foundation for the National Institutes of Health. Potential conflicts of interest. All authors: No reported conflicts. Publisher Copyright: {\textcopyright} 2014 Published by Oxford University Press on behalf of the Infectious Diseases Society of America.",
year = "2014",
month = nov,
day = "1",
doi = "10.1093/cid/ciu436",
language = "English (US)",
volume = "59",
pages = "S255--S260",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
}