Model studies of cellular excitation

Y. Rudy, H. Fozzard, E. Marban, H. Ter Keurs

Research output: Contribution to journalArticlepeer-review


A mathematical model of the cardiac ventricular cell is used to describe ionic currents and dynamic concentration changes during a normal action potential. The model is also used to study arrhythmogenic activity of the single cell including early afterdepolarizations, delayed afterdepolarizations and rhythmic (spontaneous and triggered) activity under various degrees of calcium overload.

Original languageEnglish (US)
Pages (from-to)67-77
Number of pages11
JournalAdvances in Experimental Medicine and Biology
StatePublished - 1995
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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