TY - JOUR
T1 - Mode of delivery among women with maternal cardiac disease
AU - Gavin, Nicole R.
AU - Federspiel, Jerome J.
AU - Boyer, Theresa
AU - Carey, Scott
AU - Darwin, Kristin C.
AU - Debrosse, Alexia
AU - Sharma, Garima
AU - Cedars, Ari
AU - Minhas, Anum
AU - Vaught, Arthur J.
N1 - Funding Information:
AJV received funding through the Eunice Kennedy Shriver National Institute of Child Health & Human Development Building Interdisciplinary Research in Women’s Health (BIRCWH) Award (K12-HD085845) and the Johns Hopkins University School of Medicine Robert E. Meyerhoff Professorship Award. GS is supported by Blumenthal Scholarship In Preventive Cardiology. AM was supported by the National Heart, Lung, and Blood Institute training grant T32HL007024, the Lou and Nancy Grasmick Endowed Research Fellowship and the Marie-Josée and Henry R. Kravis Endowed Fellowship. JJF was supported by the National Center for Advancing Translational Sciences via award TL1TR002555.
Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Nature America, Inc.
PY - 2023/7
Y1 - 2023/7
N2 - Objective: To determine if maternal cardiac disease affects delivery mode and to investigate maternal morbidity. Study design: Retrospective cohort study performed using electronic medical record data. Primary outcome was mode of delivery; secondary outcomes included indication for cesarean delivery, and rates of severe maternal morbidity. Results: Among 14,160 deliveries meeting inclusion criteria, 218 (1.5%) had maternal cardiac disease. Cesarean delivery was more common in women with maternal cardiac disease (adjusted odds ratio 1.63 [95% confidence interval 1.18–2.25]). Patients delivered by cesarean delivery in the setting of maternal cardiac disease had significantly higher rates of severe maternal morbidity, with a 24.38-fold higher adjusted odds of severe maternal morbidity (95% confidence interval: 10.56–54.3). Conclusion: While maternal cardiac disease was associated with increased risk of cesarean delivery, most were for obstetric indications. Additionally, cesarean delivery in the setting of maternal cardiac disease is associated with high rates of severe maternal morbidity.
AB - Objective: To determine if maternal cardiac disease affects delivery mode and to investigate maternal morbidity. Study design: Retrospective cohort study performed using electronic medical record data. Primary outcome was mode of delivery; secondary outcomes included indication for cesarean delivery, and rates of severe maternal morbidity. Results: Among 14,160 deliveries meeting inclusion criteria, 218 (1.5%) had maternal cardiac disease. Cesarean delivery was more common in women with maternal cardiac disease (adjusted odds ratio 1.63 [95% confidence interval 1.18–2.25]). Patients delivered by cesarean delivery in the setting of maternal cardiac disease had significantly higher rates of severe maternal morbidity, with a 24.38-fold higher adjusted odds of severe maternal morbidity (95% confidence interval: 10.56–54.3). Conclusion: While maternal cardiac disease was associated with increased risk of cesarean delivery, most were for obstetric indications. Additionally, cesarean delivery in the setting of maternal cardiac disease is associated with high rates of severe maternal morbidity.
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U2 - 10.1038/s41372-023-01625-4
DO - 10.1038/s41372-023-01625-4
M3 - Article
C2 - 36737572
AN - SCOPUS:85147361515
SN - 0743-8346
VL - 43
SP - 849
EP - 855
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 7
ER -