Mobile Elements: Drivers of Genome Evolution

Haig H. Kazazian

Research output: Contribution to journalReview articlepeer-review

1274 Scopus citations

Abstract

Mobile elements within genomes have driven genome evolution in diverse ways. Particularly in plants and mammals, retrotransposons have accumulated to constitute a large fraction of the genome and have shaped both genes and the entire genome. Although the host can often control their numbers, massive expansions of retrotransposons have been tolerated during evolution. Now mobile elements are becoming useful tools for learning more about genome evolution and gene function.

Original languageEnglish (US)
Pages (from-to)1626-1632
Number of pages7
JournalScience
Volume303
Issue number5664
DOIs
StatePublished - Mar 12 2004
Externally publishedYes

ASJC Scopus subject areas

  • General

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