Mitogen-activated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: Implications for cellular survival and tumor promotion

Medicine & Life Sciences

• 1,10-phenanthroline 6%
• 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone 19%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 5%
• Acetylcysteine 4%
• Butylated Hydroxytoluene 63%
• Carcinogens 4%
• Cell Survival 6%
• Dual Specificity Phosphatase 1 6%
• Extracellular Signal-Regulated MAP Kinases 19%
• fos Genes 6%
• Hydrogen Peroxide 44%
• Intercellular Signaling Peptides and Proteins 3%
• JNK Mitogen-Activated Protein Kinases 4%
• Keratinocytes 4%
• MAP Kinase Kinase Kinases 6%
• Metals 3%
• Mitogen-Activated Protein Kinase Kinases 14%
• Mitogen-Activated Protein Kinase Phosphatases 6%
• Mitogen-Activated Protein Kinases 43%
• Neoplasms 14%
• Oxidants 4%
• PC12 Cells 5%
• Proteins 1%
• Skin 2%
• Suramin 11%