Miscarriage but Not Stillbirth Rates Are Higher Among Younger Nulliparas in Rural Southern Nepal

Joanne Katz; Subarna K. Khatry; Steven C. LeClerq; Sharada R. Shrestha; Keith P. West; Parul Christian

doi:10.1016/j.jadohealth.2007.11.137

Miscarriage but Not Stillbirth Rates Are Higher Among Younger Nulliparas in Rural Southern Nepal

Joanne Katz, Subarna K. Khatry, Steven C. LeClerq, Sharada R. Shrestha, Keith P. West, Parul Christian

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Purpose: To examine the impact of young maternal age on miscarriages and stillbirths in rural Southern Nepal. Method: Pregnancies, miscarriages, and stillbirths were prospectively identified in two randomized trials of maternal micronutrient supplementation. This analysis included 5861 women of parity 0 (nulliparas) and 4459 of parity 1 (primiparas) who were <26 years of age. Results: Among nulliparous women, 5.7% and 4.6% of pregnancies ended in miscarriage and stillbirth. The adjusted relative risk of miscarriage was 2.07 for girls <15 (95% confidence interval [CI] = 1.17-3.66) compared with those 18 and 19 years, and was 1.40 (95% CI = 1.06-1.84) among those 15-17 years. Stillbirth rates did not differ significantly by maternal age. There were no differences in miscarriage or stillbirth rates by maternal age among primiparas. Conclusion: Young maternal age increased the risk of miscarriages but not stillbirths for nulliparas. Miscarriages and stillbirths did not differ by maternal age for primiparous women.

Original language	English (US)
Pages (from-to)	587-595
Number of pages	9
Journal	Journal of Adolescent Health
Volume	42
Issue number	6
DOIs	https://doi.org/10.1016/j.jadohealth.2007.11.137
State	Published - Jun 2008

Keywords

Adolescent pregnancy
Fetal loss
Miscarriage
Parity
Stillbirth

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Public Health, Environmental and Occupational Health
Psychiatry and Mental health

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10.1016/j.jadohealth.2007.11.137

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@article{31214737c7fc4aa38a46ee10530408be,

title = "Miscarriage but Not Stillbirth Rates Are Higher Among Younger Nulliparas in Rural Southern Nepal",

abstract = "Purpose: To examine the impact of young maternal age on miscarriages and stillbirths in rural Southern Nepal. Method: Pregnancies, miscarriages, and stillbirths were prospectively identified in two randomized trials of maternal micronutrient supplementation. This analysis included 5861 women of parity 0 (nulliparas) and 4459 of parity 1 (primiparas) who were <26 years of age. Results: Among nulliparous women, 5.7% and 4.6% of pregnancies ended in miscarriage and stillbirth. The adjusted relative risk of miscarriage was 2.07 for girls <15 (95% confidence interval [CI] = 1.17-3.66) compared with those 18 and 19 years, and was 1.40 (95% CI = 1.06-1.84) among those 15-17 years. Stillbirth rates did not differ significantly by maternal age. There were no differences in miscarriage or stillbirth rates by maternal age among primiparas. Conclusion: Young maternal age increased the risk of miscarriages but not stillbirths for nulliparas. Miscarriages and stillbirths did not differ by maternal age for primiparous women.",

keywords = "Adolescent pregnancy, Fetal loss, Miscarriage, Parity, Stillbirth",

author = "Joanne Katz and Khatry, {Subarna K.} and LeClerq, {Steven C.} and Shrestha, {Sharada R.} and West, {Keith P.} and Parul Christian",

note = "Funding Information: This project was supported by the US Agency for International Development (USAID) under Cooperative Agreement HRN-A-00-97-00015-00 between the Office of Health and Nutrition, USAID, Washington, DC, and the Center for Human Nutrition (CHN), Department of International Health; the Bill and Melinda Gates Foundation, Seattle, WA; the National Institutes for Health grant R03 HD049406-01;UNICEF Country Office, Kathmandu, Nepal; and the Site and Life Research Institute, Johns Hopkins University, Bloomberg School of Public Health, Baltimore. The study was a joint undertaking between the CHN and the National Society for the Prevention of Blindness, Kathmandu, Nepal. NNIPS-2 supplements were provided by Roche Basel, as part of its Task Force Sight and Life project. NNIPS-3 supplements were provided by Roche, Brazil, and were manufactured by NutriCorp International, CE Jamieson & Company Ltd, Windsor, ON, Canada. ",

year = "2008",

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doi = "10.1016/j.jadohealth.2007.11.137",

language = "English (US)",

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journal = "Journal of Adolescent Health",

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T1 - Miscarriage but Not Stillbirth Rates Are Higher Among Younger Nulliparas in Rural Southern Nepal

AU - Katz, Joanne

AU - Khatry, Subarna K.

AU - LeClerq, Steven C.

AU - Shrestha, Sharada R.

AU - West, Keith P.

AU - Christian, Parul

N1 - Funding Information: This project was supported by the US Agency for International Development (USAID) under Cooperative Agreement HRN-A-00-97-00015-00 between the Office of Health and Nutrition, USAID, Washington, DC, and the Center for Human Nutrition (CHN), Department of International Health; the Bill and Melinda Gates Foundation, Seattle, WA; the National Institutes for Health grant R03 HD049406-01;UNICEF Country Office, Kathmandu, Nepal; and the Site and Life Research Institute, Johns Hopkins University, Bloomberg School of Public Health, Baltimore. The study was a joint undertaking between the CHN and the National Society for the Prevention of Blindness, Kathmandu, Nepal. NNIPS-2 supplements were provided by Roche Basel, as part of its Task Force Sight and Life project. NNIPS-3 supplements were provided by Roche, Brazil, and were manufactured by NutriCorp International, CE Jamieson & Company Ltd, Windsor, ON, Canada.

PY - 2008/6

Y1 - 2008/6

N2 - Purpose: To examine the impact of young maternal age on miscarriages and stillbirths in rural Southern Nepal. Method: Pregnancies, miscarriages, and stillbirths were prospectively identified in two randomized trials of maternal micronutrient supplementation. This analysis included 5861 women of parity 0 (nulliparas) and 4459 of parity 1 (primiparas) who were <26 years of age. Results: Among nulliparous women, 5.7% and 4.6% of pregnancies ended in miscarriage and stillbirth. The adjusted relative risk of miscarriage was 2.07 for girls <15 (95% confidence interval [CI] = 1.17-3.66) compared with those 18 and 19 years, and was 1.40 (95% CI = 1.06-1.84) among those 15-17 years. Stillbirth rates did not differ significantly by maternal age. There were no differences in miscarriage or stillbirth rates by maternal age among primiparas. Conclusion: Young maternal age increased the risk of miscarriages but not stillbirths for nulliparas. Miscarriages and stillbirths did not differ by maternal age for primiparous women.

AB - Purpose: To examine the impact of young maternal age on miscarriages and stillbirths in rural Southern Nepal. Method: Pregnancies, miscarriages, and stillbirths were prospectively identified in two randomized trials of maternal micronutrient supplementation. This analysis included 5861 women of parity 0 (nulliparas) and 4459 of parity 1 (primiparas) who were <26 years of age. Results: Among nulliparous women, 5.7% and 4.6% of pregnancies ended in miscarriage and stillbirth. The adjusted relative risk of miscarriage was 2.07 for girls <15 (95% confidence interval [CI] = 1.17-3.66) compared with those 18 and 19 years, and was 1.40 (95% CI = 1.06-1.84) among those 15-17 years. Stillbirth rates did not differ significantly by maternal age. There were no differences in miscarriage or stillbirth rates by maternal age among primiparas. Conclusion: Young maternal age increased the risk of miscarriages but not stillbirths for nulliparas. Miscarriages and stillbirths did not differ by maternal age for primiparous women.

KW - Adolescent pregnancy

KW - Fetal loss

KW - Miscarriage

KW - Parity

KW - Stillbirth

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JO - Journal of Adolescent Health

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ER -

Miscarriage but Not Stillbirth Rates Are Higher Among Younger Nulliparas in Rural Southern Nepal

Abstract

Keywords

ASJC Scopus subject areas

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