Minimal Fat Renal Angiomyolipoma: The Initial Study with Contrast-Enhanced Ultrasonography

Qing Lu, Wenping Wang, Beijian Huang, Chaolun Li, Cong Li

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


We visualized minimal fat renal angiomyolipomas (AMLs) by contrast-enhanced ultrasonography (CEUS). Conventional ultrasound and CEUS images were retrospectively analyzed for solid minimal fat renal AML cases (n = 18) and solid renal cell carcinoma (RCC) cases (n = 105). We compared size, echogenicity and color flow signals with conventional ultrasound, and enhancement patterns with CEUS, in AMLs vs. RCCs. No significant differences in echogenicity and color flow signal existed between AMLs and RCCs using conventional ultrasound. With CEUS, slow centripetal enhancement in the cortical phase (83.3% of AMLs vs. 1.9% of RCCs) and homogeneous peak enhancement (100.0% of AMLs vs. 34.3% of RCCs) were valuable traits for differentiating these tumor types. These two CEUS-determined traits, combined, were differentiating criteria for minimal fat renal AMLs and RCCs; positive and negative predictive values were 100.0% and 97.2%, respectively. Slow centripetal enhancement in the cortical phase and homogeneous enhancement at peak are main features of CEUS-confirmed solid minimal fat renal AML.

Original languageEnglish (US)
Pages (from-to)1896-1901
Number of pages6
JournalUltrasound in Medicine and Biology
Issue number11
StatePublished - Nov 2012
Externally publishedYes


  • Angiomyolipoma
  • Contrast agent
  • Kidney
  • Minimal fat
  • Renal cell carcinoma
  • Ultrasonography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Biophysics


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