TY - GEN
T1 - Miniaturized Catheter-Integrated Photoacoustic Ablation Monitoring System
T2 - 2022 IEEE International Ultrasonics Symposium, IUS 2022
AU - Gao, Shang
AU - Rahaman, Ashiqur
AU - Ashikaga, Hiroshi
AU - Halperin, Henry R.
AU - Zhang, Haichong K.
N1 - Funding Information:
ACKNOWLEDGMENTS This work was supported by the Worcester Polytechnic Institute internal fund, the Transformative Research and Innovation, Accelerating Discovery (TRIAD) grant, and the National Institutes of Health funding [grant numbers OD028162, CA134675, R01EB022011].
Publisher Copyright:
© 2022 IEEE.
PY - 2022
Y1 - 2022
N2 - Current gold standard approach of radiofrequency ablation (RFA) utilizes computed tomography (CT) and magnetic resonance imaging (MRI) for pre- and post-operative assessments, lacking the real-time monitoring of the ablation process. Photoacoustic (PA) imaging solves this limitation by utilizing a laser-generated real-time functional imaging process, allowing an operator to observe how the ablation process is going. Nevertheless, the PA RFA essentially depends on two separate insertions of the PA imaging technique and the RFA catheter, imposing a challenge in utilizing this technique in muscular tissue. To solve this problem, we present a miniaturized catheter-integrated PA ablation monitoring system for performing the PA RFA in one insertion, where we integrated an ultrasound (US) transducer, an optical fiber, and a RFA into 4 mm in diameter. The proposed miniaturized catheter-integrated PA RFA is evaluated using an ex-vivo porcine cardiac tissue, showing the ablation monitoring by providing temporal ablation extent (AE) feedback at a wide range of PA spectrum scanning. We expect the proposed system will simplify and minimize the complication of the ablation procedure.
AB - Current gold standard approach of radiofrequency ablation (RFA) utilizes computed tomography (CT) and magnetic resonance imaging (MRI) for pre- and post-operative assessments, lacking the real-time monitoring of the ablation process. Photoacoustic (PA) imaging solves this limitation by utilizing a laser-generated real-time functional imaging process, allowing an operator to observe how the ablation process is going. Nevertheless, the PA RFA essentially depends on two separate insertions of the PA imaging technique and the RFA catheter, imposing a challenge in utilizing this technique in muscular tissue. To solve this problem, we present a miniaturized catheter-integrated PA ablation monitoring system for performing the PA RFA in one insertion, where we integrated an ultrasound (US) transducer, an optical fiber, and a RFA into 4 mm in diameter. The proposed miniaturized catheter-integrated PA RFA is evaluated using an ex-vivo porcine cardiac tissue, showing the ablation monitoring by providing temporal ablation extent (AE) feedback at a wide range of PA spectrum scanning. We expect the proposed system will simplify and minimize the complication of the ablation procedure.
KW - Necrotic Region Matmine
KW - Photoacoustic Imaging
KW - Radiofrequency Ablation
KW - Surgical Guidance
UR - https://www.scopus.com/pages/publications/85143828638
UR - https://www.scopus.com/pages/publications/85143828638#tab=citedBy
U2 - 10.1109/IUS54386.2022.9957498
DO - 10.1109/IUS54386.2022.9957498
M3 - Conference contribution
AN - SCOPUS:85143828638
T3 - IEEE International Ultrasonics Symposium, IUS
BT - IUS 2022 - IEEE International Ultrasonics Symposium
PB - IEEE Computer Society
Y2 - 10 October 2022 through 13 October 2022
ER -