Miller-Fisher syndrome mimicking intracranial hypertension following head trauma

S. Pulitanò, L. Viola, O. Genovese, A. Chiaretti, M. Piastra, P. Mariotti, F. Di Rocco, G. Polidori, C. Di Rocco

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Introduction: Miller-Fisher syndrome (MFS) is a polyneuropathy with benign outcome characterized by ophthalmoplegia, limb ataxia and tendon areflexia. Impaired consciousness level and intracranial hypertension are very rare symptoms in MFS. Case report: We describe the case of a 5-year-old girl who showed intracranial hypertension, transient coma and respiratory failure after mild head injury; moreover the patient showed mild ataxia, areflexia, ophthalmoplegia and autonomic disturbancies. These symptoms were suggestive of MFS. Electrophysiologic studies and laboratory tests confirmed the diagnosis and immunoglobulins and steroids were given. The child showed a progressive clinical improvement and the final outcome was good. Conclusion: This case, initially managed as trauma injury due to the presence of suggestive signs and clinical history, maskered an atypical presentation of Miller-Fisher syndrome, a rare disorder of central nervous system.

Original languageEnglish (US)
Pages (from-to)473-476
Number of pages4
JournalChild's Nervous System
Issue number6
StatePublished - Jun 2005
Externally publishedYes


  • Bickerstaff's encephalitis
  • Brain injury
  • Intracranial hypertension
  • Miller Fisher syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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