Middle molecule mass spectrometry (a review)

Catherine Fenselau, Robert Cotter, Gordon Hansen, Tom Chen, David Heller

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


This paper reviews some recent advances in the application of mass spectrometry to the analysis of middle molecules in the mass range of 1000 to 10,000 daltons, and of very polar molecules (organic salts). The quantitative analysis of components of mixtures will be illustrated, carried out by creating a spectrum which consists primarily of molecular ion species whose relative intensities correspond to the relative molar concentrations of the various components.

Original languageEnglish (US)
Pages (from-to)21-30
Number of pages10
JournalJournal of Chromatography A
Issue numberC
StatePublished - Nov 20 1981

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry


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