Microstructurally based model analysis of γ‐irradiated tendon allografts

S. M. Belkoff, R. C. Haut

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


A mathematical model of the collagenous microstructure of tendon was used to analyze the mechanical responses of γ‐irradiated patellar tendon allografts and nonirradiated controls. The model was fit to tensile test response curves from 10 pairs of allografts. Donors ranged in age from 16–64 years (six males, four females). The model indicated a decrease in elastic modulus of irradiated tendon collagen. It also suggested a significant increase in the degree and range of collagen fiber crimping following γ irradiation. The model results agree with the literature and histological observations. The model fit the experimental response curves well and provided a structurally based, objective method of quantitatively studying the mechanical response of tendons and the consequences of irradiation sterilization.

Original languageEnglish (US)
Pages (from-to)461-464
Number of pages4
JournalJournal of Orthopaedic Research
Issue number3
StatePublished - May 1992


  • Allograft
  • Irradiation sterilization
  • Microstructural model
  • Patellar tendon

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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