Microscopic hemodynamics and hemorheology with the immersed-boundary lattice-boltzmann method

J. Zhang; P. C. Johnson; A. S. Popel

doi:10.1201/EBK1439820056

Microscopic hemodynamics and hemorheology with the immersed-boundary lattice-boltzmann method

J. Zhang, P. C. Johnson, A. S. Popel

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Red blood cells are the most important constituents of blood due to their physiological importance and hemodynamic significance. To study the motion of red blood cells in the microcirculation, an immersed-boundary/lattice- Boltzmann method is developed integrating fluid flow and membrane mechanics, and also accounting for cell aggregation. A detailed description of the computational modules is provided, including a lattice-Boltzmann method for fluid mechanics, an immersed-boundary method for fluid-membrane interaction, an explicit fluid property updating algorithm, and a Morse potential for modeling intercellular aggregation. Simulations are presented for several flow configurations to demonstrate the potentiality and usefulness of the computational approach.

Original language	English (US)
Title of host publication	Computational Hydrodynamics of Capsules and Biological Cells
Publisher	CRC Press
Pages	113-148
Number of pages	36
ISBN (Electronic)	9781439820063
ISBN (Print)	9781439820056
DOIs	https://doi.org/10.1201/EBK1439820056
State	Published - Jan 1 2010

ASJC Scopus subject areas

Mathematics(all)
Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)
Physics and Astronomy(all)

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10.1201/EBK1439820056

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abstract = "Red blood cells are the most important constituents of blood due to their physiological importance and hemodynamic significance. To study the motion of red blood cells in the microcirculation, an immersed-boundary/lattice- Boltzmann method is developed integrating fluid flow and membrane mechanics, and also accounting for cell aggregation. A detailed description of the computational modules is provided, including a lattice-Boltzmann method for fluid mechanics, an immersed-boundary method for fluid-membrane interaction, an explicit fluid property updating algorithm, and a Morse potential for modeling intercellular aggregation. Simulations are presented for several flow configurations to demonstrate the potentiality and usefulness of the computational approach.",

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N2 - Red blood cells are the most important constituents of blood due to their physiological importance and hemodynamic significance. To study the motion of red blood cells in the microcirculation, an immersed-boundary/lattice- Boltzmann method is developed integrating fluid flow and membrane mechanics, and also accounting for cell aggregation. A detailed description of the computational modules is provided, including a lattice-Boltzmann method for fluid mechanics, an immersed-boundary method for fluid-membrane interaction, an explicit fluid property updating algorithm, and a Morse potential for modeling intercellular aggregation. Simulations are presented for several flow configurations to demonstrate the potentiality and usefulness of the computational approach.

AB - Red blood cells are the most important constituents of blood due to their physiological importance and hemodynamic significance. To study the motion of red blood cells in the microcirculation, an immersed-boundary/lattice- Boltzmann method is developed integrating fluid flow and membrane mechanics, and also accounting for cell aggregation. A detailed description of the computational modules is provided, including a lattice-Boltzmann method for fluid mechanics, an immersed-boundary method for fluid-membrane interaction, an explicit fluid property updating algorithm, and a Morse potential for modeling intercellular aggregation. Simulations are presented for several flow configurations to demonstrate the potentiality and usefulness of the computational approach.

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Microscopic hemodynamics and hemorheology with the immersed-boundary lattice-boltzmann method

Abstract

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