Microbiota that affect risk for shigellosis in children in low-income countries

Brianna Lindsay, Joe Oundo, M. Anowar Hossain, Martin Antonio, Boubou Tamboura, Alan W. Walker, Joseph N. Paulson, Julian Parkhill, Richard Omore, Abu S. Faruque, Suman Kumar Das, Usman N. Ikumapayi, Mitchell Adeyemi, Doh Sanogo, Debasish Saha, Samba Sow, Tamer H. Farag, Dilruba Nasrin, Shan Li, Sandra PanchalingamMyron M. Levine, Karen Kotloff, Laurence S. Magder, Laura Hungerford, Halvor Sommerfelt, Mihai Pop, James P. Nataro, O. Colin Stine

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Pathogens in the gastrointestinal tract exist within a vast population of microbes. We examined associations between pathogens and composition of gut microbiota as they relate to Shigella spp./enteroinvasive Escherichia coli infection. We analyzed 3,035 stool specimens (1,735 nondiarrheal and 1,300 moderate-to-severe diarrheal) from the Global Enteric Multicenter Study for 9 enteropathogens. Diarrheal specimens had a higher number of enteropathogens (diarrheal mean 1.4, nondiarrheal mean 0.95; p

Original languageEnglish (US)
Pages (from-to)242-250
Number of pages9
JournalEmerging Infectious Diseases
Volume21
Issue number2
DOIs
StatePublished - 2015
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Epidemiology

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