Microbial keratitis associated with contaminated ocular medications

Oliver D. Schein; Paul J. Wasson; S. Arthur Boruchoff; Kenneth R. Kenyon

doi:10.1016/0002-9394(88)90298-X

Microbial keratitis associated with contaminated ocular medications

Oliver D. Schein, Paul J. Wasson, S. Arthur Boruchoff, Kenneth R. Kenyon

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

We studied seven cases of severe gramnegative microbial keratitis associated with the use of contaminated topical ocular medications. Five cases involved Pseudomonas aeruginosa, one involved Serratia marcescens, and one involved Proteus mirabilis. In each case the same organism was cultured from corneal scrapings and from the medication. Either prednisolone acetate (one case) or timolol maleate (seven cases) was implicated in all instances.

Original language	English (US)
Pages (from-to)	361-365
Number of pages	5
Journal	American journal of ophthalmology
Volume	105
Issue number	4
DOIs	https://doi.org/10.1016/0002-9394(88)90298-X
State	Published - Apr 15 1988
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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title = "Microbial keratitis associated with contaminated ocular medications",

abstract = "We studied seven cases of severe gramnegative microbial keratitis associated with the use of contaminated topical ocular medications. Five cases involved Pseudomonas aeruginosa, one involved Serratia marcescens, and one involved Proteus mirabilis. In each case the same organism was cultured from corneal scrapings and from the medication. Either prednisolone acetate (one case) or timolol maleate (seven cases) was implicated in all instances.",

author = "Schein, {Oliver D.} and Wasson, {Paul J.} and {Arthur Boruchoff}, S. and Kenyon, {Kenneth R.}",

note = "Funding Information: From the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, and the Eye Research Institute of Retina Foundation (Dr. Kenyon), Boston, Massachusetts. Dr. Schein is a 1987-1988 Heed Ophthalmic Fellow. This study was supported in part by National Institutes of Health grant EY05799 (Dr. Kenyon). Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",

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doi = "10.1016/0002-9394(88)90298-X",

language = "English (US)",

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T1 - Microbial keratitis associated with contaminated ocular medications

AU - Schein, Oliver D.

AU - Wasson, Paul J.

AU - Arthur Boruchoff, S.

AU - Kenyon, Kenneth R.

N1 - Funding Information: From the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, and the Eye Research Institute of Retina Foundation (Dr. Kenyon), Boston, Massachusetts. Dr. Schein is a 1987-1988 Heed Ophthalmic Fellow. This study was supported in part by National Institutes of Health grant EY05799 (Dr. Kenyon). Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

PY - 1988/4/15

Y1 - 1988/4/15

N2 - We studied seven cases of severe gramnegative microbial keratitis associated with the use of contaminated topical ocular medications. Five cases involved Pseudomonas aeruginosa, one involved Serratia marcescens, and one involved Proteus mirabilis. In each case the same organism was cultured from corneal scrapings and from the medication. Either prednisolone acetate (one case) or timolol maleate (seven cases) was implicated in all instances.

AB - We studied seven cases of severe gramnegative microbial keratitis associated with the use of contaminated topical ocular medications. Five cases involved Pseudomonas aeruginosa, one involved Serratia marcescens, and one involved Proteus mirabilis. In each case the same organism was cultured from corneal scrapings and from the medication. Either prednisolone acetate (one case) or timolol maleate (seven cases) was implicated in all instances.

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Microbial keratitis associated with contaminated ocular medications

Abstract

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