Abstract
Due to their low cost compatibility with replication-based fabrication methods, thermoplastics represent an exceptionally attractive family of materials for the fabrication of lab-on-A-chip platforms. A diverse range of thermoplastic materials suitable for micro fluidic fabrication is available, offering a wide selection of mechanical and chemical properties that can be leveraged and further tailored for speci fi c applications. While highthroughput embossing methods such as reel-To-reel processing of thermoplastics is an attractive method for industrial micro fluidic chip production, the use of single chip hot embossing is a cost-effective technique for realizing high-quality micro fluidic devices during the prototyping stage. Here we describe methods for the replication of microscale features in two thermoplastics, polymethylmethacrylate (PMMA) and polycarbonate (PC), using hot embossing from a silicon template fabricated by deep reactive-ion etching.
Original language | English (US) |
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Title of host publication | Microfluidic Diagnostics |
Subtitle of host publication | Methods and Protocols |
Publisher | Humana Press Inc. |
Pages | 115-123 |
Number of pages | 9 |
ISBN (Print) | 9781627031332 |
DOIs | |
State | Published - 2013 |
Externally published | Yes |
Publication series
Name | Methods in Molecular Biology |
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Volume | 949 |
ISSN (Print) | 1064-3745 |
Keywords
- Hot embossing
- Imprinting
- Polycarbonate
- Polymethylmethacrylate
- Replication
- Thermoplastics
ASJC Scopus subject areas
- Molecular Biology
- Genetics