Methods: Genetic Epidemiology

Research output: Contribution to journalReview articlepeer-review


Given the potential benefits of gene identification in psychiatry, genetic epidemiology has become a mainstream discipline within the field. This article discusses the main tools for gene discovery. The focus is on the designs and analytic approaches for each of these methods. Because most gene discovery has now moved to genetic association studies, and most recently to genome-wide association studies, the focus is on methods for this design. Also highlighted are the current challenges of genetic epidemiology as a prelude to future approaches that may be applied to psychiatric disorders in the coming years.

Original languageEnglish (US)
Pages (from-to)795-814
Number of pages20
JournalClinics in laboratory medicine
Issue number4
StatePublished - Dec 2010


  • Genetic epidemiology
  • Genome-wide association studies
  • Linkage studies
  • Polymorphisms

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical


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