Methods and Challenges in Quantitative Imaging Biomarker Development

Richard G. Abramson; Kirsteen R. Burton; John Paul J. Yu; Ernest M. Scalzetti; Thomas E. Yankeelov; Andrew B. Rosenkrantz; Mishal Mendiratta-Lala; Brian J. Bartholmai; Dhakshinamoorthy Ganeshan; Leon Lenchik; Rathan M. Subramaniam

doi:10.1016/j.acra.2014.09.001

Methods and Challenges in Quantitative Imaging Biomarker Development

Richard G. Abramson, Kirsteen R. Burton, John Paul J. Yu, Ernest M. Scalzetti, Thomas E. Yankeelov, Andrew B. Rosenkrantz, Mishal Mendiratta-Lala, Brian J. Bartholmai, Dhakshinamoorthy Ganeshan, Leon Lenchik, Rathan M. Subramaniam

School of Medicine

Research output: Contribution to journal › Review article › peer-review

47 Scopus citations

Abstract

Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.

Original language	English (US)
Pages (from-to)	25-32
Number of pages	8
Journal	Academic radiology
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/j.acra.2014.09.001
State	Published - Jan 1 2015

Keywords

Biomarker development
Quantitative imaging
Radiology

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.acra.2014.09.001

Cite this

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title = "Methods and Challenges in Quantitative Imaging Biomarker Development",

abstract = "Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.",

keywords = "Biomarker development, Quantitative imaging, Radiology",

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AU - Yu, John Paul J.

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AU - Yankeelov, Thomas E.

AU - Rosenkrantz, Andrew B.

AU - Mendiratta-Lala, Mishal

AU - Bartholmai, Brian J.

AU - Ganeshan, Dhakshinamoorthy

AU - Lenchik, Leon

AU - Subramaniam, Rathan M.

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AB - Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.

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Methods and Challenges in Quantitative Imaging Biomarker Development

Abstract

Keywords

ASJC Scopus subject areas

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