TY - GEN
T1 - Methodology for assessing the degree of degeneration of the porcine intervertebral discs based on magnetic resonance imaging
AU - Lipiński, Seweryn
AU - Jezierska-Woźniak, Katarzyna
AU - Habich, Aleksandra
AU - Barczewska, Monika
AU - Wojtkiewicz, Joanna
AU - Walczak, Piotr
AU - Maksymowicz, Wojciech
N1 - Publisher Copyright:
© Springer Science+Business Media Singapore 2016.
PY - 2016
Y1 - 2016
N2 - Degeneration of intervertebral discs can lead to various health problems, among which low back pain is the most common. Studies concerning methods of dealing with that problem are being conducted and magnetic resonance imaging is one of the most popular methods of assessing their progress. Many of these studies are based on animal models. The paper links these two facts and so it contains the description of methodology that can be used for assessing the degree of degeneration of the porcine intervertebral discs based on scans obtained in MRI study. Proposed method uses Otsu method of automatic thresholding and next basic operators of morphological image processing. The outcome is binary mask giving direct information about locations of intervertebral discs in MRI scans. The obtained mask can be also used to separate locations of intervertebral discs in following MRI studies of the same animals, in cases where they are much harder to delineate due to their degeneration. The paper shows also exemplary results demonstrating usefulness of proposed methodology for the evaluation of discs treatment using mesenchymal stem cells.
AB - Degeneration of intervertebral discs can lead to various health problems, among which low back pain is the most common. Studies concerning methods of dealing with that problem are being conducted and magnetic resonance imaging is one of the most popular methods of assessing their progress. Many of these studies are based on animal models. The paper links these two facts and so it contains the description of methodology that can be used for assessing the degree of degeneration of the porcine intervertebral discs based on scans obtained in MRI study. Proposed method uses Otsu method of automatic thresholding and next basic operators of morphological image processing. The outcome is binary mask giving direct information about locations of intervertebral discs in MRI scans. The obtained mask can be also used to separate locations of intervertebral discs in following MRI studies of the same animals, in cases where they are much harder to delineate due to their degeneration. The paper shows also exemplary results demonstrating usefulness of proposed methodology for the evaluation of discs treatment using mesenchymal stem cells.
KW - Animal model
KW - Intervertebral discs degeneration
KW - Magnetic resonance imaging
KW - Morphological image processing
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U2 - 10.1007/978-981-287-817-5_87
DO - 10.1007/978-981-287-817-5_87
M3 - Conference contribution
AN - SCOPUS:84946024596
SN - 9789812878168
T3 - IFMBE Proceedings
SP - 399
EP - 402
BT - 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food and Environmental Technologies, WC 2015
A2 - Kramar, Peter
A2 - Jarm, Tomaž
PB - Springer Verlag
T2 - 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food and Environmental Technologies, WC 2015
Y2 - 6 September 2015 through 10 September 2015
ER -