Metastatic lung adenocarcinoma to the iris mimicking cogan-reese syndrome

Ben J. Harvey; Hans E. Grossniklaus; Matthew P. Traynor; Steven R. Sarkisian; Donald U. Stone

doi:10.1097/IJG.0b013e3182208a2e

Metastatic lung adenocarcinoma to the iris mimicking cogan-reese syndrome

Ben J. Harvey, Hans E. Grossniklaus, Matthew P. Traynor, Steven R. Sarkisian, Donald U. Stone

School of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

PURPOSE: Case report of metastatic lung cancer to the iris mimicking Cogan-Reese syndrome. METHODS: A 61-year-old female with a history of non-small cell lung cancer presented with unilateral elevated intraocular pressure (IOP) and multiple hyperpigmented iris nodules associated with an anterior iris membrane. The patient's IOP could not be controlled medically, so she underwent trabeculectomy with simultaneous iris biopsy. RESULTS: Histopathology revealed proliferation of glandular epithelium on the iris surface consistent with metastatic lung adenocarcinoma. CONCLUSIONS: Iris metastases have varied presentations, and one must consider metastatic disease in any patient with a history of cancer presenting with iris lesions. The formation of an iris membrane and nodules by metastatic adenocarcinoma to the iris may mimic Cogan-Reese syndrome.

Original language	English (US)
Pages (from-to)	567-569
Number of pages	3
Journal	Journal of glaucoma
Volume	21
Issue number	8
DOIs	https://doi.org/10.1097/IJG.0b013e3182208a2e
State	Published - Oct 1 2012

Keywords

Cogan-Reese syndrome
metastases
secondary glaucoma

ASJC Scopus subject areas

Ophthalmology

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10.1097/IJG.0b013e3182208a2e

Cite this

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title = "Metastatic lung adenocarcinoma to the iris mimicking cogan-reese syndrome",

abstract = "PURPOSE: Case report of metastatic lung cancer to the iris mimicking Cogan-Reese syndrome. METHODS: A 61-year-old female with a history of non-small cell lung cancer presented with unilateral elevated intraocular pressure (IOP) and multiple hyperpigmented iris nodules associated with an anterior iris membrane. The patient's IOP could not be controlled medically, so she underwent trabeculectomy with simultaneous iris biopsy. RESULTS: Histopathology revealed proliferation of glandular epithelium on the iris surface consistent with metastatic lung adenocarcinoma. CONCLUSIONS: Iris metastases have varied presentations, and one must consider metastatic disease in any patient with a history of cancer presenting with iris lesions. The formation of an iris membrane and nodules by metastatic adenocarcinoma to the iris may mimic Cogan-Reese syndrome.",

keywords = "Cogan-Reese syndrome, metastases, secondary glaucoma",

author = "Harvey, {Ben J.} and Grossniklaus, {Hans E.} and Traynor, {Matthew P.} and Sarkisian, {Steven R.} and Stone, {Donald U.}",

year = "2012",

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doi = "10.1097/IJG.0b013e3182208a2e",

language = "English (US)",

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journal = "Journal of Glaucoma",

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T1 - Metastatic lung adenocarcinoma to the iris mimicking cogan-reese syndrome

AU - Harvey, Ben J.

AU - Grossniklaus, Hans E.

AU - Traynor, Matthew P.

AU - Sarkisian, Steven R.

AU - Stone, Donald U.

PY - 2012/10/1

Y1 - 2012/10/1

N2 - PURPOSE: Case report of metastatic lung cancer to the iris mimicking Cogan-Reese syndrome. METHODS: A 61-year-old female with a history of non-small cell lung cancer presented with unilateral elevated intraocular pressure (IOP) and multiple hyperpigmented iris nodules associated with an anterior iris membrane. The patient's IOP could not be controlled medically, so she underwent trabeculectomy with simultaneous iris biopsy. RESULTS: Histopathology revealed proliferation of glandular epithelium on the iris surface consistent with metastatic lung adenocarcinoma. CONCLUSIONS: Iris metastases have varied presentations, and one must consider metastatic disease in any patient with a history of cancer presenting with iris lesions. The formation of an iris membrane and nodules by metastatic adenocarcinoma to the iris may mimic Cogan-Reese syndrome.

AB - PURPOSE: Case report of metastatic lung cancer to the iris mimicking Cogan-Reese syndrome. METHODS: A 61-year-old female with a history of non-small cell lung cancer presented with unilateral elevated intraocular pressure (IOP) and multiple hyperpigmented iris nodules associated with an anterior iris membrane. The patient's IOP could not be controlled medically, so she underwent trabeculectomy with simultaneous iris biopsy. RESULTS: Histopathology revealed proliferation of glandular epithelium on the iris surface consistent with metastatic lung adenocarcinoma. CONCLUSIONS: Iris metastases have varied presentations, and one must consider metastatic disease in any patient with a history of cancer presenting with iris lesions. The formation of an iris membrane and nodules by metastatic adenocarcinoma to the iris may mimic Cogan-Reese syndrome.

KW - Cogan-Reese syndrome

KW - metastases

KW - secondary glaucoma

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Metastatic lung adenocarcinoma to the iris mimicking cogan-reese syndrome

Abstract

Keywords

ASJC Scopus subject areas

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