Metastatic lung adenocarcinoma to the iris mimicking cogan-reese syndrome

Ben J. Harvey, Hans E. Grossniklaus, Matthew P. Traynor, Steven R. Sarkisian, Donald U. Stone

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


PURPOSE: Case report of metastatic lung cancer to the iris mimicking Cogan-Reese syndrome. METHODS: A 61-year-old female with a history of non-small cell lung cancer presented with unilateral elevated intraocular pressure (IOP) and multiple hyperpigmented iris nodules associated with an anterior iris membrane. The patient's IOP could not be controlled medically, so she underwent trabeculectomy with simultaneous iris biopsy. RESULTS: Histopathology revealed proliferation of glandular epithelium on the iris surface consistent with metastatic lung adenocarcinoma. CONCLUSIONS: Iris metastases have varied presentations, and one must consider metastatic disease in any patient with a history of cancer presenting with iris lesions. The formation of an iris membrane and nodules by metastatic adenocarcinoma to the iris may mimic Cogan-Reese syndrome.

Original languageEnglish (US)
Pages (from-to)567-569
Number of pages3
JournalJournal of glaucoma
Issue number8
StatePublished - Oct 1 2012


  • Cogan-Reese syndrome
  • metastases
  • secondary glaucoma

ASJC Scopus subject areas

  • Ophthalmology


Dive into the research topics of 'Metastatic lung adenocarcinoma to the iris mimicking cogan-reese syndrome'. Together they form a unique fingerprint.

Cite this